Publications

Eunha Kim†, Jun R. Huh, Gloria B. Choi† (2024) Pre and Postnatal Neuro-immune Interactions in Neurodevelopmental Disorders. Nature Immunology (Invited review article) (†co- corresponding authors)

Taeyong Lee and Eunha Kim (2024) Etiologies underlying sex bias in autism spectrum disorder: a narrative review using preclinical rodent models. The Ewha Medical Journal (Invited review article) Accepted

Seoyeon Kim, Jihae Lee, In Gyeong Koh, Jungeun Ji, Hyun Jung Kim, Eunha Kim, Jihwan Park, Jong-Eun Park, Joon-Young An (2024) An integrative single-cell atlas to explore the cellular and temporal specificity of neurological disorder genes during human brain development. bioRxiv

Dong Sun Oh*, Eunha Kim*, Guangqing Lu*, Rachelly Normand*, Lydia L. Shook, Amanda Lyall, Olyvia Jasset, Stepan Demidkin, Emily Gilbert, Joon Kim, Babatunde Akinwunmi, Jessica Tantivit, Alice Tirard, Benjamin Y. Arnold, Kamil Slowikowski, MGH COVID-19 Collection & Processing Team, Marcia B. Goldberg, Michael R. Filbin, Nir Hacohen, Long H. Nguyen, Andrew T. Chan, Xu G. Yu, Jonathan Z. Li, Lael Yonker, Alessio Fasano, Roy H. Perlis, Ofer Pasternak, Kathryn J. Gray, Gloria B. Choi, David A. Drew, Pritha Sen†, Alexandra-Chloé Villani†, Andrea G. Edlow†, Jun R. Huh† (2024) SARS-CoV-2 infection elucidates unique features of pregnancy-specific immunity. medRxiv (*equally contributed to this work) (†co-corresponding authors)

Youjin Oh, Eun-Seon Yoo, Sang Hyeon Ju, Eunha Kim, Seulgi Lee, Seyun Kim, Kevin Wickman, Jong-Woo Sohn (2023) GIRK2 potassium channels expressed by the AgRP neurons decrease adiposity and body weight in mice. Plos Biology 21(8):e3002252

Haein Lee, Eunha Kim, Seyun Kim (2023) miRNA-induced Downregulation of IPMK in Macrophages Mediates Lipopolysaccharid-Triggered TLR4 Signaling. Biomolecules 13(2):332

Eunha Kim†, Melissa Tran, Yanyi Sun, Jun R. Huh† (2022) Isolation and analyses of lamina propria lymphocytes from mouse intestines. STAR Protocols 3(2):101366 (†co-corresponding authors)

Eunha Kim*, Donggi Paik*, Ricardo N. Ramirez, Delaney G. Biggs, Youngjun Park, Ho-Keun Kwon, Gloria B. Choi†, Jun R. Huh† (2022) Maternal gut bacteria drive intestinal inflammation in offspring with neurodevelopmental disorders by altering the chromatin landscape of CD4+ T cells. Immunity 55(1):145-158(Featured article) (*equally contributed to this work) (†co-corresponding authors)
- Highlighted in Preview: Kristine E. Zengeler & John R. Lukens (2022) Maternal inflammation is hard for offspring to stomach. Immunity 55(1):6-8

Donggi Paik*, Lina Yao*, Yancong Zhang, Sena Bae, Gabriel D. D’Agostino, Eunha Kim, Eric A. Franzosa, Julina Avila-Pacheco, Jordan E. Bisanz, Christopher K. Rakowshi, Hera Vlamakis, Ramnik J. Xavier, Peter J. Turnbaugh, Randy S. Longman, Michael R. Krout, Clary B. Clish, Curtis Huttenhower, Jun R. Huh†, A. Sloan Devilin† (2021) Human gut bacteria produce Th17-modulating bile acid metabolites. Nature 603:907-912(*equally contributed to this work) (†co-corresponding authors)

Brian T. Kalish*†, Eunha Kim*, Benjamin Finander, Erin E. Duffy, Hyunju Kim, Casey K. Gilman, Yeong ShinYim, Lilin Tong, Randal J. Kaufman, Eric C. Griffith, Gloria B. Choi, Michael E. Greenberg†, Jun R. Huh†(2021) Maternal Immune Activation in Mice Disrupts Proteostasis in the Fetal Brain. Nature Neuroscience 24:204-213 (*equally contributed to this work) (†co-corresponding authors)
- Highlighted in News and Views: Kristine E. Zengeler & John R. Lukens (2021) Inflammation stresses out brain development. Nature Neuroscience 24:155-157

Hyunki Kim*, Byoung-Ha Yoon*, Chang-Myung Oh*, Joonyub Lee*, Kanghoon Lee, Heein Song, Eunha Kim, Kijong Yi, Mi-Young Kim, Hyeongseok Kim, Yong Kyung Kim, Eun-Hye Seo, Haejeong Heo, Hee-jin Kim, Junguee Lee, Jae Myoung Suh, Seung-Hoi Koo, Je Kyung Seong, Seyun Kim, Young Seok Ju, Minho Shong, Mirang Kim†, Hail Kim† (2020) PRMT1 is required for the maintenance of mature β-Cell identity. Diabetes 69(3):355-368 (*equally contributed to this work) (†co-corresponding authors)

Saiyu Hang*, Donggi Paik*, Lina Yao, Eunha Kim, Trinath Jamma, Jingping Lu, Soyoung Ha, Brandon N. Nelson, Samantha P. Kelly, Lin Wu, Ye Zheng, Randy S. Longman, Fraydoon Rastinejad, A. Sloan Develin, Michael R. Krout, Michael A. Fischbach†, Dan R. Littman†, Jun R. Huh† (2020) Bile acid metabolites control Th17 and Treg cell differentiation. Nature 576:143-148 (*equally contributed to this work) (†co-corresponding authors)

Eunha Kim and Jun R. Huh (2019) NMD Takes the Immune Road to NDD. Neuron 104(4): 625-626 (Invited preview)

Wooseob Kim, Eunha Kim, Hyungyu Min, Min Gyu Kim, Verena B. Eisenbeis, Amit K. Dutta, Igor Palvlovic, Henning J. Jessen, Seyun Kim†, and Rho Hyun Seong† (2019) Inositol polyphosphates promote T cell-independent humoral immunity via the regulation of Bruton’s tyrosine kinase. Proceedings of the National Academy of Sciences of the U.S.A. 116(26): 12952-12957 (†co-corresponding authors)

Eunha Kim, Jiyoon Beon, Seulgi Lee, Seung Ju Park, Hyoungjoon Ahn, Min Gyu Kim, Jeong Eun Park, Wooseob Kim, Jae-Min Yuk, Suk-Jo Kang, Seung-Hyo Lee, Eun-Kyeong Jo, Rho Hyun Seong† and Seyun Kim† (2017). Inositol polyphosphate multikinase promotes Toll-like receptor-induced inflammation by stabilizing TRAF6. Science Advances 3, e1602296. (†co-corresponding authors)

Eunha Kim, Hyoungjoon Ahn, Min-Gyu Kim, Haein Lee and Seyun Kim (2017) The expanding significance of inositol polyphosphate multikinase as a signaling hub. Molecules and Cells 40(5): 315-321 (Invited review article)

Dong Eon Kim*, Mi-Jin Jang*, Young Ran Kim*, Joo-Young Lee, Eun Byul Cho, Eunha Kim, Yeji Kim, Mi Young Kim, Won-il Jeong, Seyun Kim†, Yong-Mahn Han†, Seung-Hyo Lee† (2017) Prediction of drug-induced immune-mediated hepatotoxicity using hepatocyte-like cells derived from human embryonic stem cells. Toxicology 387: 1-9. (*equally contributed to this work) (†co-corresponding authors)

Eunha Kim, Jiyoon Beon, Seulgi Lee, Jina Park and Seyun Kim (2016) IPMK: A versatile regulator of nuclear signaling events. Advances in Biological Regulation 61: 25-32. (Invited review article)

Eunha Kim*, Richa Tyagi*, Joo-Young Lee, Jina Park, Young-ran Kim, Po Yu Chen, Jiyoung Y. Cha,Solomon H. Snyder† and Seyun Kim† (2013) Inositol polyphosphate multikinase is a coactivator for serum response factor-dependent induction of immediate early genes. Proceedings of the National Academy of Sciences of the U.S.A. 110(49): 19938-19943 (*equally contributed to this work) (†co-corresponding authors)

Sun-Woo Kim, Kun-Young Park, Bobae Kim, Eunha Kim and Chang-Kee Hyun (2013) Lactobacillus rhamnosus GG improves insulin sensitivity and reduces adiposity in high-fat diet-fed mice through enhancement of adiponectin production. Biochemical and Biophysical Research Communications 431(2): 258-263.

Yoo Jeong Lee, Eun Hee Ko, Ji Eun Kim, Eunha Kim, Hyemin Lee, Hyeonjin Choi, Jung Hwan Yu, HyoJung Kim, Je-Kyung Seong, Kyung-Sup Kim and Jae-woo Kim (2012) Nuclear receptor PPARγ-regulated monoacylglycerol O-acyltransferase 1 (MGAT1) expression in responsible for the lipid accumulation in diet-induced hepatic steatosis. Proceedings of the National Academy of Sciences of the U.S.A. 109(34): 13656-13661.


Eunha Kim, Jung-Han Lee, James M. Ntambi and Chang-Kee Hyun (2011) Inhibition of stearoyl-CoA desaturase 1 activates AMPK and exhibits beneficial lipid metabolic effects in vitro. European Journal of Pharmacology 672(1-3): 38-44.

Eun-Do Kim, Eunha Kim, Jung-Han Lee and Chang-Kee Hyun (2011) Gly-Ala-Gly-Val-Gly-Tyr, a novel synthetic peptide, improves glucose transport and exerts beneficial lipid metabolic effects in 3T3-L1 adipocytes. European Journal of Pharmacology 650(1): 479-485.

Chang-Kee Hyun, Eun-Do Kim, Matthew T. Flowers, Xueqing Liu, Eunha Kim, Maggie Strable and JamesM. Ntambi (2010) Adipose-specific deletion of stearoyl-CoA desaturase 1 up-regulates the glucose transporter GLUT1 in adipose tissue. Biochemical and Biophysical Research Communications 399(4):480-486.